Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FDXRNADPH:adrenodoxin oxidoreductase, mitochondrial. (532 aa)    
Predicted Functional Partners:
FDX1
Ferredoxin 1.
    
 0.977
LOC105740713
2Fe-2S ferredoxin-type domain-containing protein.
    
 0.952
FDX2
2Fe-2S ferredoxin-type domain-containing protein.
    
 0.916
ENSNLEP00000048186
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
     
 0.874
CYP11B2
Cytochrome P450 family 11 subfamily B member 2; Belongs to the cytochrome P450 family.
     
 0.830
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
    
 0.762
CYP24A1
Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family.
     
 0.735
CYP27A1
Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.
     
 0.701
CYP27B1
Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family.
     
 0.697
DPYD
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.
  
 0.685
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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