STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSK3AGlycogen synthase kinase 3 alpha. (439 aa)    
Predicted Functional Partners:
AXIN1
Axin 1.
   
 0.929
CTNNB1
Catenin beta 1.
    
 0.904
FRAT2
FRAT regulator of WNT signaling pathway 2.
    
 0.874
APC
APC regulator of WNT signaling pathway.
    
 0.850
JUP
Junction plakoglobin.
    
 0.846
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.839
AXIN2
DIX domain-containing protein.
   
 0.810
ENSNLEP00000029616
RGS domain-containing protein.
   
 0.810
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.797
APC2
APC regulator of WNT signaling pathway 2.
    
 0.789
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.