STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF4Interferon regulatory factor 4. (451 aa)    
Predicted Functional Partners:
SPI1
Spi-1 proto-oncogene.
   
 
 0.933
BATF
Basic leucine zipper ATF-like transcription factor.
   
 
 0.862
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.839
STAT6
Signal transducer and activator of transcription.
   
 0.834
STAT3
Signal transducer and activator of transcription.
   
 0.809
BCL6
BCL6 transcription repressor.
    
 0.762
PRDM1
PR/SET domain 1.
   
 
 0.744
PAX5
Paired box 5.
   
  
 0.744
PPARGC1A
PPARG coactivator 1 alpha.
   
 0.721
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.716
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.