Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)    
Predicted Functional Partners:
EED
Embryonic ectoderm development.
   
 0.998
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.998
EZH1
Uncharacterized protein.
   
 0.997
AEBP2
AE binding protein 2.
    
 0.993
JARID2
Jumonji and AT-rich interaction domain containing 2.
    
 0.991
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 0.988
MTF2
Metal response element binding transcription factor 2.
   
 0.987
PHF19
PHD finger protein 19.
   
 0.984
PHF1
PHD finger protein 1.
   
 0.983
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.965
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.