Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACTC1Actin alpha cardiac muscle 1. (377 aa)    
Predicted Functional Partners:
TNNI3
Troponin I3, cardiac type.
   
 0.983
MYH7
Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.983
TNNT2
Uncharacterized protein.
   
 0.983
TPM1
Uncharacterized protein; Belongs to the tropomyosin family.
   
 0.974
MYL2
Myosin light chain 2.
   
 0.960
MYL3
EF-hand domain-containing protein.
   
 0.955
MYL4
Myosin light chain 4.
   
 0.953
TPM3
Uncharacterized protein; Belongs to the tropomyosin family.
   
 0.940
TPM2
Tropomyosin 2; Belongs to the tropomyosin family.
   
 0.931
ACTA1
Actin alpha 1, skeletal muscle.
   
   0.886
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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