SCLY protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SCLY

Selenocysteine lyase. (418 aa)

Predicted Functional Partners:

ISCU

0.984

SEPHS2

0.961

SEPHS1

0.948

TXNRD2

0.920

TXNRD1

0.920

TXNRD3

0.919

LYRM4

0.887

NFU1

0.801

ENSNLEP00000032560

0.801

FXN

0.796

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSNLEP00000032560	FXN	ENSNLEP00000032560	ENSNLEP00000029001	Nfu_N domain-containing protein.	Uncharacterized protein.	0.505
ENSNLEP00000032560	ISCU	ENSNLEP00000032560	ENSNLEP00000008273	Nfu_N domain-containing protein.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.797
ENSNLEP00000032560	LYRM4	ENSNLEP00000032560	ENSNLEP00000034901	Nfu_N domain-containing protein.	LYR motif containing 4; Belongs to the complex I LYR family.	0.408
ENSNLEP00000032560	SCLY	ENSNLEP00000032560	ENSNLEP00000013604	Nfu_N domain-containing protein.	Selenocysteine lyase.	0.801
FXN	ENSNLEP00000032560	ENSNLEP00000029001	ENSNLEP00000032560	Uncharacterized protein.	Nfu_N domain-containing protein.	0.505
FXN	ISCU	ENSNLEP00000029001	ENSNLEP00000008273	Uncharacterized protein.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.916
FXN	LYRM4	ENSNLEP00000029001	ENSNLEP00000034901	Uncharacterized protein.	LYR motif containing 4; Belongs to the complex I LYR family.	0.930
FXN	NFU1	ENSNLEP00000029001	ENSNLEP00000012318	Uncharacterized protein.	NFU1 iron-sulfur cluster scaffold.	0.505
FXN	SCLY	ENSNLEP00000029001	ENSNLEP00000013604	Uncharacterized protein.	Selenocysteine lyase.	0.796
ISCU	ENSNLEP00000032560	ENSNLEP00000008273	ENSNLEP00000032560	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Nfu_N domain-containing protein.	0.797
ISCU	FXN	ENSNLEP00000008273	ENSNLEP00000029001	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Uncharacterized protein.	0.916
ISCU	LYRM4	ENSNLEP00000008273	ENSNLEP00000034901	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	LYR motif containing 4; Belongs to the complex I LYR family.	0.992
ISCU	NFU1	ENSNLEP00000008273	ENSNLEP00000012318	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	NFU1 iron-sulfur cluster scaffold.	0.797
ISCU	SCLY	ENSNLEP00000008273	ENSNLEP00000013604	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Selenocysteine lyase.	0.984
LYRM4	ENSNLEP00000032560	ENSNLEP00000034901	ENSNLEP00000032560	LYR motif containing 4; Belongs to the complex I LYR family.	Nfu_N domain-containing protein.	0.408
LYRM4	FXN	ENSNLEP00000034901	ENSNLEP00000029001	LYR motif containing 4; Belongs to the complex I LYR family.	Uncharacterized protein.	0.930
LYRM4	ISCU	ENSNLEP00000034901	ENSNLEP00000008273	LYR motif containing 4; Belongs to the complex I LYR family.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.992
LYRM4	NFU1	ENSNLEP00000034901	ENSNLEP00000012318	LYR motif containing 4; Belongs to the complex I LYR family.	NFU1 iron-sulfur cluster scaffold.	0.408
LYRM4	SCLY	ENSNLEP00000034901	ENSNLEP00000013604	LYR motif containing 4; Belongs to the complex I LYR family.	Selenocysteine lyase.	0.887
NFU1	FXN	ENSNLEP00000012318	ENSNLEP00000029001	NFU1 iron-sulfur cluster scaffold.	Uncharacterized protein.	0.505

page 1 of 3

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About