| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HGS | PTPN23 | ENSNLEP00000016808 | ENSNLEP00000007674 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Protein tyrosine phosphatase non-receptor type 23. | 0.845 |
| HGS | STAM | ENSNLEP00000016808 | ENSNLEP00000046424 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule. | 0.999 |
| HGS | STAM2 | ENSNLEP00000016808 | ENSNLEP00000013744 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule 2. | 0.999 |
| HGS | TSG101 | ENSNLEP00000016808 | ENSNLEP00000021594 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.998 |
| HGS | USP8 | ENSNLEP00000016808 | ENSNLEP00000007642 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. | 0.959 |
| JAK1 | JAK2 | ENSNLEP00000018412 | ENSNLEP00000010932 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.995 |
| JAK1 | JAK3 | ENSNLEP00000018412 | ENSNLEP00000007120 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.995 |
| JAK1 | STAM | ENSNLEP00000018412 | ENSNLEP00000046424 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.928 |
| JAK1 | STAM2 | ENSNLEP00000018412 | ENSNLEP00000013744 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.961 |
| JAK1 | TYK2 | ENSNLEP00000018412 | ENSNLEP00000014804 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.974 |
| JAK2 | JAK1 | ENSNLEP00000010932 | ENSNLEP00000018412 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.995 |
| JAK2 | JAK3 | ENSNLEP00000010932 | ENSNLEP00000007120 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.957 |
| JAK2 | STAM | ENSNLEP00000010932 | ENSNLEP00000046424 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.950 |
| JAK2 | STAM2 | ENSNLEP00000010932 | ENSNLEP00000013744 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.945 |
| JAK2 | TYK2 | ENSNLEP00000010932 | ENSNLEP00000014804 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.984 |
| JAK3 | JAK1 | ENSNLEP00000007120 | ENSNLEP00000018412 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.995 |
| JAK3 | JAK2 | ENSNLEP00000007120 | ENSNLEP00000010932 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.957 |
| JAK3 | STAM | ENSNLEP00000007120 | ENSNLEP00000046424 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.953 |
| JAK3 | STAM2 | ENSNLEP00000007120 | ENSNLEP00000013744 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.961 |
| JAK3 | TYK2 | ENSNLEP00000007120 | ENSNLEP00000014804 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.956 |
