Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGF2RInsulin like growth factor 2 receptor. (2458 aa)    
Predicted Functional Partners:
M6PR
Mannose-6-phosphate receptor, cation dependent.
     
 0.996
IGF2
IlGF domain-containing protein.
    
 
 0.963
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.960
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.956
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
    
 
 0.948
PLIN3
Perilipin; Belongs to the perilipin family.
   
 0.886
ENSNLEP00000027009
Uncharacterized protein.
    
 
 0.856
GAK
Cyclin G associated kinase.
   
 
 0.852
VPS26A
VPS26, retromer complex component A.
    
 
 0.792
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
   
 0.767
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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