STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM10ADAM metallopeptidase domain 10. (748 aa)    
Predicted Functional Partners:
ADAM17
ADAM metallopeptidase domain 17.
     
0.938
EFNA2
Ephrin RBD domain-containing protein; Belongs to the ephrin family.
    
 0.852
TSPAN14
Tetraspanin.
   
 0.838
DLG1
Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.
   
 
 0.817
NOTCH1
Notch receptor 1.
    
 0.791
TSPAN15
Tetraspanin 15; Belongs to the tetraspanin (TM4SF) family.
    
 0.782
UNC5C
Unc-5 netrin receptor C.
      
 0.761
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
     
 0.753
APP
Amyloid beta precursor protein.
    
 0.751
AKAP9
A-kinase anchoring protein 9.
      
 0.740
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.