STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE10APhosphodiesterase. (734 aa)    
Predicted Functional Partners:
PDE5A
Phosphodiesterase.
  
 
0.695
ALDH7A1
Aldedh domain-containing protein.
      
 0.689
PDE7A
Phosphodiesterase.
   
0.629
PPP1R1B
Protein phosphatase 1 regulatory inhibitor subunit 1B.
     
 0.612
PDE4A
Phosphodiesterase.
    
0.591
GUCY2C
Guanylate cyclase.
   
 0.513
PDE7B
Phosphodiesterase.
   
0.512
GNG7
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 
 0.481
PRKX
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.457
LOC100592070
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 0.457
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.