Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PRKG1cGMP-dependent protein kinase. (686 aa)    
Predicted Functional Partners:
MRVI1
Murine retrovirus integration site 1 homolog.
   
 0.994
FBXL7
F-box and leucine rich repeat protein 7.
   
  
 0.975
VASP
Vasodilator stimulated phosphoprotein.
    
 0.970
PPP1R12A
Protein phosphatase 1 regulatory subunit.
    
 0.952
PRKG2
cGMP-dependent protein kinase.
  
  
 
0.946
CREB1
cAMP responsive element binding protein 1.
    
 0.942
RGS2
Regulator of G protein signaling 2.
    
 0.939
PPP1R17
Protein phosphatase 1 regulatory subunit 17.
    
 0.939
KCNMA1
Potassium calcium-activated channel subfamily M alpha 1.
   
 
 0.937
PLN
Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
   
 0.936
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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