STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PALB2Partner and localizer of BRCA2. (1186 aa)    
Predicted Functional Partners:
BRCA2
BRCA2 DNA repair associated.
   
 0.999
BRCA1
BRCA1 DNA repair associated.
   
 0.999
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.995
RAD51C
RAD51 paralog C.
  
 0.994
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.988
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
 0.982
NDUFB5
NADH:ubiquinone oxidoreductase subunit B5.
   
 0.979
NDUFB10
NADH:ubiquinone oxidoreductase subunit B10.
   
 0.976
NDUFC2
NDUFC2-KCTD14 readthrough.
   
 0.973
NDUFS3
NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family.
   
 0.971
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.