| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATM | ATR | ENSNLEP00000008823 | ENSNLEP00000025629 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.961 |
| ATM | TELO2 | ENSNLEP00000008823 | ENSNLEP00000010606 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Telomere maintenance 2. | 0.862 |
| ATM | TTI1 | ENSNLEP00000008823 | ENSNLEP00000007653 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | TELO2 interacting protein 1. | 0.772 |
| ATM | TTI2 | ENSNLEP00000008823 | ENSNLEP00000014702 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | TELO2 interacting protein 2. | 0.523 |
| ATR | ATM | ENSNLEP00000025629 | ENSNLEP00000008823 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.961 |
| ATR | TELO2 | ENSNLEP00000025629 | ENSNLEP00000010606 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Telomere maintenance 2. | 0.986 |
| ATR | TTI1 | ENSNLEP00000025629 | ENSNLEP00000007653 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | TELO2 interacting protein 1. | 0.588 |
| ATR | TTI2 | ENSNLEP00000025629 | ENSNLEP00000014702 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | TELO2 interacting protein 2. | 0.512 |
| BTBD8 | PTRH2 | ENSNLEP00000012680 | ENSNLEP00000000922 | BTB domain containing 8. | Peptidyl-tRNA hydrolase 2. | 0.576 |
| BTBD8 | TTI2 | ENSNLEP00000012680 | ENSNLEP00000014702 | BTB domain containing 8. | TELO2 interacting protein 2. | 0.499 |
| DUSP27 | TTI2 | ENSNLEP00000017980 | ENSNLEP00000014702 | Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | TELO2 interacting protein 2. | 0.486 |
| ENSNLEP00000038558 | RUVBL2 | ENSNLEP00000038558 | ENSNLEP00000005920 | Uncharacterized protein. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.978 |
| ENSNLEP00000038558 | TELO2 | ENSNLEP00000038558 | ENSNLEP00000010606 | Uncharacterized protein. | Telomere maintenance 2. | 0.805 |
| ENSNLEP00000038558 | TTI1 | ENSNLEP00000038558 | ENSNLEP00000007653 | Uncharacterized protein. | TELO2 interacting protein 1. | 0.774 |
| ENSNLEP00000038558 | TTI2 | ENSNLEP00000038558 | ENSNLEP00000014702 | Uncharacterized protein. | TELO2 interacting protein 2. | 0.530 |
| MAK16 | TTI2 | ENSNLEP00000034500 | ENSNLEP00000014702 | Protein MAK16 homolog; Belongs to the MAK16 family. | TELO2 interacting protein 2. | 0.563 |
| PTRH2 | BTBD8 | ENSNLEP00000000922 | ENSNLEP00000012680 | Peptidyl-tRNA hydrolase 2. | BTB domain containing 8. | 0.576 |
| PTRH2 | TTI2 | ENSNLEP00000000922 | ENSNLEP00000014702 | Peptidyl-tRNA hydrolase 2. | TELO2 interacting protein 2. | 0.489 |
| RUVBL2 | ENSNLEP00000038558 | ENSNLEP00000005920 | ENSNLEP00000038558 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | Uncharacterized protein. | 0.978 |
| RUVBL2 | TELO2 | ENSNLEP00000005920 | ENSNLEP00000010606 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | Telomere maintenance 2. | 0.793 |
