| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F2 | FURIN | ENSNLEP00000017190 | ENSNLEP00000014749 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | 0.843 |
| F2 | PROC | ENSNLEP00000017190 | ENSNLEP00000032013 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Protein C, inactivator of coagulation factors Va and VIIIa; Belongs to the peptidase S1 family. | 0.984 |
| F2 | PROS1 | ENSNLEP00000017190 | ENSNLEP00000002105 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Protein S. | 0.491 |
| FURIN | F2 | ENSNLEP00000014749 | ENSNLEP00000017190 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.843 |
| FURIN | MMP11 | ENSNLEP00000014749 | ENSNLEP00000000617 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Matrix metallopeptidase 11. | 0.853 |
| FURIN | MMP14 | ENSNLEP00000014749 | ENSNLEP00000017957 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Matrix metallopeptidase 14. | 0.893 |
| FURIN | MMP15 | ENSNLEP00000014749 | ENSNLEP00000004082 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Matrix metallopeptidase 15. | 0.833 |
| FURIN | NOTCH1 | ENSNLEP00000014749 | ENSNLEP00000010158 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Notch receptor 1. | 0.880 |
| FURIN | PDGFB | ENSNLEP00000014749 | ENSNLEP00000018484 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.806 |
| FURIN | PROC | ENSNLEP00000014749 | ENSNLEP00000032013 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Protein C, inactivator of coagulation factors Va and VIIIa; Belongs to the peptidase S1 family. | 0.816 |
| FURIN | PROS1 | ENSNLEP00000014749 | ENSNLEP00000002105 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Protein S. | 0.792 |
| FURIN | RIN3 | ENSNLEP00000014749 | ENSNLEP00000020842 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Ras and Rab interactor 3. | 0.852 |
| FURIN | TGFB1 | ENSNLEP00000014749 | ENSNLEP00000016659 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.808 |
| MMP11 | FURIN | ENSNLEP00000000617 | ENSNLEP00000014749 | Matrix metallopeptidase 11. | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | 0.853 |
| MMP14 | FURIN | ENSNLEP00000017957 | ENSNLEP00000014749 | Matrix metallopeptidase 14. | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | 0.893 |
| MMP14 | MMP15 | ENSNLEP00000017957 | ENSNLEP00000004082 | Matrix metallopeptidase 14. | Matrix metallopeptidase 15. | 0.591 |
| MMP14 | TGFB1 | ENSNLEP00000017957 | ENSNLEP00000016659 | Matrix metallopeptidase 14. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.466 |
| MMP15 | FURIN | ENSNLEP00000004082 | ENSNLEP00000014749 | Matrix metallopeptidase 15. | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | 0.833 |
| MMP15 | MMP14 | ENSNLEP00000004082 | ENSNLEP00000017957 | Matrix metallopeptidase 15. | Matrix metallopeptidase 14. | 0.591 |
| NOTCH1 | FURIN | ENSNLEP00000010158 | ENSNLEP00000014749 | Notch receptor 1. | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | 0.880 |
