STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (785 aa)    
Predicted Functional Partners:
ADAM17
ADAM metallopeptidase domain 17.
     
 0.830
MMP11
Matrix metallopeptidase 11.
    
 0.787
MMP14
Matrix metallopeptidase 14.
    
 0.784
COL23A1
Uncharacterized protein.
    
 0.772
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.763
PACS1
Phosphofurin acidic cluster sorting protein 1.
    
 
 0.752
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
   
 0.744
RIN3
Ras and Rab interactor 3.
    
 
 0.726
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
   
 
 0.714
COL25A1
Collagen type XXV alpha 1 chain.
    
 0.710
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.