STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF5Interferon regulatory factor 5. (509 aa)    
Predicted Functional Partners:
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.879
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.876
STAT1
Signal transducer and activator of transcription.
   
 0.765
ENSNLEP00000039390
Protein kinase domain-containing protein.
   
 0.725
STAT4
Signal transducer and activator of transcription.
   
 0.705
TYK2
Tyrosine-protein kinase.
   
 0.675
STAT2
Signal transducer and activator of transcription.
   
 0.638
TLR8
Toll like receptor 8; Belongs to the Toll-like receptor family.
   
 
 0.631
TNFAIP3
TNF alpha induced protein 3.
   
  
 0.624
PTPN22
Protein tyrosine phosphatase non-receptor type 22.
   
 0.619
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.