STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IBTKInhibitor of Bruton tyrosine kinase. (1353 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.905
BTK
Tyrosine-protein kinase.
   
 0.820
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.655
CACUL1
CDK2 associated cullin domain 1; Belongs to the cullin family.
   
 0.605
POP7
Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family.
    
   0.589
RPP25L
Ribonuclease P/MRP subunit p25 like.
    
   0.571
ZC3H14
Zinc finger CCCH-type containing 14.
      
 0.459
EIF4A1
Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family.
    
   0.457
ENSNLEP00000025854
Uncharacterized protein; Belongs to the DEAD box helicase family.
    
   0.457
ENSNLEP00000028230
Uncharacterized protein; Belongs to the DEAD box helicase family.
    
   0.457
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.