| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSNLEP00000048701 | HGS | ENSNLEP00000048701 | ENSNLEP00000016808 | VPS37 C-terminal domain-containing protein. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.899 |
| ENSNLEP00000048701 | STAM | ENSNLEP00000048701 | ENSNLEP00000046424 | VPS37 C-terminal domain-containing protein. | Signal transducing adaptor molecule. | 0.944 |
| ENSNLEP00000048701 | STAM2 | ENSNLEP00000048701 | ENSNLEP00000013744 | VPS37 C-terminal domain-containing protein. | Signal transducing adaptor molecule 2. | 0.782 |
| ENSNLEP00000048701 | TSG101 | ENSNLEP00000048701 | ENSNLEP00000021594 | VPS37 C-terminal domain-containing protein. | Tumor susceptibility 101. | 0.972 |
| ENSNLEP00000048701 | VPS28 | ENSNLEP00000048701 | ENSNLEP00000013013 | VPS37 C-terminal domain-containing protein. | VPS28 N-terminal domain-containing protein; Belongs to the VPS28 family. | 0.979 |
| ENSNLEP00000048701 | VPS37A | ENSNLEP00000048701 | ENSNLEP00000034729 | VPS37 C-terminal domain-containing protein. | VPS37A subunit of ESCRT-I. | 0.544 |
| HGS | ENSNLEP00000048701 | ENSNLEP00000016808 | ENSNLEP00000048701 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37 C-terminal domain-containing protein. | 0.899 |
| HGS | STAM | ENSNLEP00000016808 | ENSNLEP00000046424 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule. | 0.999 |
| HGS | STAM2 | ENSNLEP00000016808 | ENSNLEP00000013744 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule 2. | 0.999 |
| HGS | TSG101 | ENSNLEP00000016808 | ENSNLEP00000021594 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.998 |
| HGS | VPS28 | ENSNLEP00000016808 | ENSNLEP00000013013 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS28 N-terminal domain-containing protein; Belongs to the VPS28 family. | 0.969 |
| HGS | VPS37A | ENSNLEP00000016808 | ENSNLEP00000034729 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37A subunit of ESCRT-I. | 0.899 |
| JAK2 | JAK3 | ENSNLEP00000010932 | ENSNLEP00000007120 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.957 |
| JAK2 | STAM | ENSNLEP00000010932 | ENSNLEP00000046424 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.950 |
| JAK2 | STAM2 | ENSNLEP00000010932 | ENSNLEP00000013744 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.945 |
| JAK3 | JAK2 | ENSNLEP00000007120 | ENSNLEP00000010932 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.957 |
| JAK3 | STAM | ENSNLEP00000007120 | ENSNLEP00000046424 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.953 |
| JAK3 | STAM2 | ENSNLEP00000007120 | ENSNLEP00000013744 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.961 |
| STAM | ENSNLEP00000048701 | ENSNLEP00000046424 | ENSNLEP00000048701 | Signal transducing adaptor molecule. | VPS37 C-terminal domain-containing protein. | 0.944 |
| STAM | HGS | ENSNLEP00000046424 | ENSNLEP00000016808 | Signal transducing adaptor molecule. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.999 |
