Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NESIF rod domain-containing protein; Belongs to the intermediate filament family. (1230 aa)    
Predicted Functional Partners:
NEFM
IF rod domain-containing protein; Belongs to the intermediate filament family.
    
 0.927
GFAP
IF rod domain-containing protein; Belongs to the intermediate filament family.
    
 
 0.916
VIM
IF rod domain-containing protein; Belongs to the intermediate filament family.
    
 
 0.864
PRPH
Peripherin; Belongs to the intermediate filament family.
    
   0.786
DES
Desmin; Belongs to the intermediate filament family.
    
 
 0.744
DCX
Doublecortin.
      
 0.711
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.702
BDNF
Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
      
 0.700
SOX17
SRY-box transcription factor 17.
    
 
 0.696
FOXA2
Fork-head domain-containing protein.
      
 0.690
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.