| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IL13RA1 | IL1B | ENSNLEP00000018021 | ENSNLEP00000044905 | Interleukin 13 receptor subunit alpha 1. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.457 |
| IL13RA1 | IL2 | ENSNLEP00000018021 | ENSNLEP00000011484 | Interleukin 13 receptor subunit alpha 1. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.767 |
| IL13RA1 | IL2RG | ENSNLEP00000018021 | ENSNLEP00000001373 | Interleukin 13 receptor subunit alpha 1. | Fibronectin type-III domain-containing protein. | 0.526 |
| IL13RA1 | IL4 | ENSNLEP00000018021 | ENSNLEP00000015527 | Interleukin 13 receptor subunit alpha 1. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. | 0.994 |
| IL13RA1 | IL4R | ENSNLEP00000018021 | ENSNLEP00000014201 | Interleukin 13 receptor subunit alpha 1. | Interleukin 4 receptor. | 0.999 |
| IL13RA1 | IL7 | ENSNLEP00000018021 | ENSNLEP00000041342 | Interleukin 13 receptor subunit alpha 1. | Interleukin 7. | 0.783 |
| IL13RA1 | IL9 | ENSNLEP00000018021 | ENSNLEP00000010091 | Interleukin 13 receptor subunit alpha 1. | Interleukin 9. | 0.729 |
| IL13RA1 | JAK3 | ENSNLEP00000018021 | ENSNLEP00000007120 | Interleukin 13 receptor subunit alpha 1. | Tyrosine-protein kinase. | 0.762 |
| IL13RA1 | STAT6 | ENSNLEP00000018021 | ENSNLEP00000021135 | Interleukin 13 receptor subunit alpha 1. | Signal transducer and activator of transcription. | 0.820 |
| IL1B | IL13RA1 | ENSNLEP00000044905 | ENSNLEP00000018021 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 13 receptor subunit alpha 1. | 0.457 |
| IL1B | IL2 | ENSNLEP00000044905 | ENSNLEP00000011484 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.948 |
| IL1B | IL2RG | ENSNLEP00000044905 | ENSNLEP00000001373 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Fibronectin type-III domain-containing protein. | 0.462 |
| IL1B | IL4 | ENSNLEP00000044905 | ENSNLEP00000015527 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. | 0.934 |
| IL1B | IL4R | ENSNLEP00000044905 | ENSNLEP00000014201 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 4 receptor. | 0.579 |
| IL1B | IL7 | ENSNLEP00000044905 | ENSNLEP00000041342 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 7. | 0.694 |
| IL1B | IL9 | ENSNLEP00000044905 | ENSNLEP00000010091 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 9. | 0.715 |
| IL1B | JAK3 | ENSNLEP00000044905 | ENSNLEP00000007120 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Tyrosine-protein kinase. | 0.408 |
| IL1B | STAT6 | ENSNLEP00000044905 | ENSNLEP00000021135 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Signal transducer and activator of transcription. | 0.547 |
| IL2 | IL13RA1 | ENSNLEP00000011484 | ENSNLEP00000018021 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | Interleukin 13 receptor subunit alpha 1. | 0.767 |
| IL2 | IL1B | ENSNLEP00000011484 | ENSNLEP00000044905 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.948 |