Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)    
Predicted Functional Partners:
NFKBIA
NFKB inhibitor alpha.
    
 0.999
IKBKG
NEMO domain-containing protein.
   
 0.999
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
  
0.999
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.998
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.998
RELA
RELA proto-oncogene, NF-kB subunit.
    
 0.998
RIPK1
Receptor interacting serine/threonine kinase 1.
   
0.997
TNFRSF1A
TNF receptor superfamily member 1A.
   
 0.997
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
   
0.997
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.996
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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