DENND5A protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DENND5A

Uncharacterized protein. (823 aa)

Predicted Functional Partners:

RAB6A

0.891

ENSNLEP00000042675

0.801

RAB6B

0.607

ENSNLEP00000030749

0.584

SNX1

0.567

CHM

0.467

GCC2

0.436

DENND4C

0.435

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHM	DENND5A	ENSNLEP00000028284	ENSNLEP00000015997	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Uncharacterized protein.	0.467
CHM	ENSNLEP00000030749	ENSNLEP00000028284	ENSNLEP00000030749	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Uncharacterized protein.	0.531
CHM	ENSNLEP00000042675	ENSNLEP00000028284	ENSNLEP00000042675	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Uncharacterized protein.	0.587
CHM	RAB6A	ENSNLEP00000028284	ENSNLEP00000020764	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB6A, member RAS oncogene family.	0.539
CHM	RAB6B	ENSNLEP00000028284	ENSNLEP00000004426	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB6B, member RAS oncogene family.	0.536
DENND4C	DENND5A	ENSNLEP00000041122	ENSNLEP00000015997	DENN domain containing 4C.	Uncharacterized protein.	0.435
DENND5A	CHM	ENSNLEP00000015997	ENSNLEP00000028284	Uncharacterized protein.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.467
DENND5A	DENND4C	ENSNLEP00000015997	ENSNLEP00000041122	Uncharacterized protein.	DENN domain containing 4C.	0.435
DENND5A	ENSNLEP00000030749	ENSNLEP00000015997	ENSNLEP00000030749	Uncharacterized protein.	Uncharacterized protein.	0.584
DENND5A	ENSNLEP00000042675	ENSNLEP00000015997	ENSNLEP00000042675	Uncharacterized protein.	Uncharacterized protein.	0.801
DENND5A	GCC2	ENSNLEP00000015997	ENSNLEP00000013286	Uncharacterized protein.	GRIP and coiled-coil domain containing 2.	0.436
DENND5A	RAB6A	ENSNLEP00000015997	ENSNLEP00000020764	Uncharacterized protein.	RAB6A, member RAS oncogene family.	0.891
DENND5A	RAB6B	ENSNLEP00000015997	ENSNLEP00000004426	Uncharacterized protein.	RAB6B, member RAS oncogene family.	0.607
DENND5A	SNX1	ENSNLEP00000015997	ENSNLEP00000035129	Uncharacterized protein.	Sorting nexin 1.	0.567
ENSNLEP00000030749	CHM	ENSNLEP00000030749	ENSNLEP00000028284	Uncharacterized protein.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.531
ENSNLEP00000030749	DENND5A	ENSNLEP00000030749	ENSNLEP00000015997	Uncharacterized protein.	Uncharacterized protein.	0.584
ENSNLEP00000030749	GCC2	ENSNLEP00000030749	ENSNLEP00000013286	Uncharacterized protein.	GRIP and coiled-coil domain containing 2.	0.728
ENSNLEP00000042675	CHM	ENSNLEP00000042675	ENSNLEP00000028284	Uncharacterized protein.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.587
ENSNLEP00000042675	DENND5A	ENSNLEP00000042675	ENSNLEP00000015997	Uncharacterized protein.	Uncharacterized protein.	0.801
ENSNLEP00000042675	RAB6A	ENSNLEP00000042675	ENSNLEP00000020764	Uncharacterized protein.	RAB6A, member RAS oncogene family.	0.663

page 1 of 2

Server load: medium (54%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About