STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FMR1Fragile X mental retardation 1. (632 aa)    
Predicted Functional Partners:
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.993
FXR2
FMR1 autosomal homolog 2.
  
 
0.992
FXR1
FMR1 autosomal homolog 1.
  
 
0.990
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.985
TDRD3
Tudor domain containing 3.
    
 
 0.936
NUFIP2
Nuclear FMR1 interacting protein 2.
   
 
 0.886
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 
 0.877
AGO1
Argonaute RISC component 1; Belongs to the argonaute family.
    
 
 0.837
DICER1
Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.
    
 
 0.822
MAP1B
Microtubule associated protein 1B.
    
 
 0.790
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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