Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RABGEF1RAB guanine nucleotide exchange factor 1. (497 aa)    
Predicted Functional Partners:
RAB5A
RAB5A, member RAS oncogene family.
   
 0.983
RAB5C
RAB5C, member RAS oncogene family.
   
 0.983
RAB5B
Uncharacterized protein.
   
 0.983
RABEP1
Rabaptin, RAB GTPase binding effector protein 1.
   
 0.951
RABEP2
Uncharacterized protein.
   
 0.936
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
   
 0.884
ALS2
Alsin Rho guanine nucleotide exchange factor ALS2.
   
 0.879
RAB24
RAB24, member RAS oncogene family.
   
 0.857
RAB20
RAB20, member RAS oncogene family.
   
 0.846
RAB22A
Uncharacterized protein.
   
 0.846
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.