Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRKACAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)    
Predicted Functional Partners:
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
  
0.997
PRKAR1A
Protein kinase cAMP-dependent type I regulatory subunit alpha.
 
 
 0.997
PRKAR2B
Protein kinase cAMP-dependent type II regulatory subunit beta.
 
 
 0.994
PRKAR2A
Protein kinase cAMP-dependent type II regulatory subunit alpha.
 
 
 0.989
PRKAR1B
Protein kinase cAMP-dependent type I regulatory subunit beta.
   
 0.985
PRKACG
Uncharacterized protein.
  
0.985
AKAP1
A-kinase anchoring protein 1.
    
 0.984
GPR161
G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family.
    
 0.958
AKAP11
A-kinase anchoring protein 11.
   
 
 0.944
MAPT
Microtubule-associated protein.
    
 
 0.938
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (16%) [HD]