STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)    
Predicted Functional Partners:
IKBKG
NEMO domain-containing protein.
   
 0.999
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
   
 0.999
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
   
 0.999
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.999
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
   
 0.999
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
   
0.996
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.996
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.996
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.996
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
   
 0.995
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.