STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THTyrosine hydroxylase. (507 aa)    
Predicted Functional Partners:
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
 
 0.845
PCBD1
Pterin-4 alpha-carbinolamine dehydratase 1.
  
 0.824
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 0.797
DBH
Dopamine beta-hydroxylase.
   
  
 0.794
SLC18A2
Solute carrier family 18 member A2.
    
 
 0.776
DDC
Dopa decarboxylase.
   
 0.766
GCH1
GTP cyclohydrolase 1.
   
 
 0.762
SLC6A3
Solute carrier family 6 member 3.
   
  
 0.760
PNMT
Phenylethanolamine N-methyltransferase.
      
 0.734
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.711
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.