STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM17ADAM metallopeptidase domain 17. (824 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.973
ADAM10
ADAM metallopeptidase domain 10.
     
0.938
NOTCH2
Notch receptor 2.
    
 0.914
RHBDF2
Rhomboid 5 homolog 2.
    
 0.901
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
     
 0.849
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
     
 0.830
ACE2
Angiotensin-converting enzyme.
   
  
 0.810
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
      
 0.792
TGFA
Transforming growth factor alpha.
   
 
 0.782
ARL11
ADP ribosylation factor like GTPase 11; Belongs to the small GTPase superfamily. Arf family.
     
 0.770
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.