| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHMP2A | HGS | ENSNLEP00000027425 | ENSNLEP00000016808 | Charged multivesicular body protein 2A. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.979 |
| CHMP2A | STAM | ENSNLEP00000027425 | ENSNLEP00000046424 | Charged multivesicular body protein 2A. | Signal transducing adaptor molecule. | 0.544 |
| CHMP2A | TSG101 | ENSNLEP00000027425 | ENSNLEP00000021594 | Charged multivesicular body protein 2A. | Tumor susceptibility 101. | 0.910 |
| CHMP2A | USP8 | ENSNLEP00000027425 | ENSNLEP00000007642 | Charged multivesicular body protein 2A. | Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. | 0.460 |
| CHMP2A | VPS28 | ENSNLEP00000027425 | ENSNLEP00000013013 | Charged multivesicular body protein 2A. | VPS28 N-terminal domain-containing protein; Belongs to the VPS28 family. | 0.944 |
| CLTC | EGFR | ENSNLEP00000001008 | ENSNLEP00000035792 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | Receptor protein-tyrosine kinase. | 0.572 |
| CLTC | EPS15 | ENSNLEP00000001008 | ENSNLEP00000044546 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | Epidermal growth factor receptor pathway substrate 15. | 0.870 |
| CLTC | HGS | ENSNLEP00000001008 | ENSNLEP00000016808 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.938 |
| CLTC | LOC101176233 | ENSNLEP00000001008 | ENSNLEP00000047166 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | Uncharacterized protein. | 0.870 |
| CLTC | STAM | ENSNLEP00000001008 | ENSNLEP00000046424 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | Signal transducing adaptor molecule. | 0.878 |
| CLTC | STAM2 | ENSNLEP00000001008 | ENSNLEP00000013744 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | Signal transducing adaptor molecule 2. | 0.662 |
| EGFR | CLTC | ENSNLEP00000035792 | ENSNLEP00000001008 | Receptor protein-tyrosine kinase. | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | 0.572 |
| EGFR | EPS15 | ENSNLEP00000035792 | ENSNLEP00000044546 | Receptor protein-tyrosine kinase. | Epidermal growth factor receptor pathway substrate 15. | 0.960 |
| EGFR | HGS | ENSNLEP00000035792 | ENSNLEP00000016808 | Receptor protein-tyrosine kinase. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.967 |
| EGFR | LOC101176233 | ENSNLEP00000035792 | ENSNLEP00000047166 | Receptor protein-tyrosine kinase. | Uncharacterized protein. | 0.892 |
| EGFR | STAM | ENSNLEP00000035792 | ENSNLEP00000046424 | Receptor protein-tyrosine kinase. | Signal transducing adaptor molecule. | 0.653 |
| EGFR | STAM2 | ENSNLEP00000035792 | ENSNLEP00000013744 | Receptor protein-tyrosine kinase. | Signal transducing adaptor molecule 2. | 0.887 |
| EGFR | USP8 | ENSNLEP00000035792 | ENSNLEP00000007642 | Receptor protein-tyrosine kinase. | Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. | 0.993 |
| EPS15 | CLTC | ENSNLEP00000044546 | ENSNLEP00000001008 | Epidermal growth factor receptor pathway substrate 15. | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | 0.870 |
| EPS15 | EGFR | ENSNLEP00000044546 | ENSNLEP00000035792 | Epidermal growth factor receptor pathway substrate 15. | Receptor protein-tyrosine kinase. | 0.960 |
