Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)    
Predicted Functional Partners:
ENO1
Enolase 1.
  
 0.981
ENSNLEP00000048318
Uncharacterized protein.
  
 0.981
ENO3
Enolase 3.
  
 0.977
ENO2
Enolase 2.
  
 0.971
ENO4
Enolase 4.
  
 0.969
LOC100586354
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.961
LDHA
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.961
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.956
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.954
LDHB
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.954
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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