| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASP10 | CASP8 | ENSNLEP00000008472 | ENSNLEP00000040588 | Caspase 10; Belongs to the peptidase C14A family. | Caspase 8; Belongs to the peptidase C14A family. | 0.997 |
| CASP10 | CFLAR | ENSNLEP00000008472 | ENSNLEP00000008469 | Caspase 10; Belongs to the peptidase C14A family. | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | 0.998 |
| CASP10 | DEDD | ENSNLEP00000008472 | ENSNLEP00000017056 | Caspase 10; Belongs to the peptidase C14A family. | Death effector domain containing. | 0.571 |
| CASP10 | FADD | ENSNLEP00000008472 | ENSNLEP00000012731 | Caspase 10; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.999 |
| CASP8 | CASP10 | ENSNLEP00000040588 | ENSNLEP00000008472 | Caspase 8; Belongs to the peptidase C14A family. | Caspase 10; Belongs to the peptidase C14A family. | 0.997 |
| CASP8 | CFLAR | ENSNLEP00000040588 | ENSNLEP00000008469 | Caspase 8; Belongs to the peptidase C14A family. | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | 0.998 |
| CASP8 | DEDD | ENSNLEP00000040588 | ENSNLEP00000017056 | Caspase 8; Belongs to the peptidase C14A family. | Death effector domain containing. | 0.764 |
| CASP8 | FADD | ENSNLEP00000040588 | ENSNLEP00000012731 | Caspase 8; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.999 |
| CFLAR | CASP10 | ENSNLEP00000008469 | ENSNLEP00000008472 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | Caspase 10; Belongs to the peptidase C14A family. | 0.998 |
| CFLAR | CASP8 | ENSNLEP00000008469 | ENSNLEP00000040588 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | Caspase 8; Belongs to the peptidase C14A family. | 0.998 |
| CFLAR | DEDD | ENSNLEP00000008469 | ENSNLEP00000017056 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | Death effector domain containing. | 0.590 |
| CFLAR | FADD | ENSNLEP00000008469 | ENSNLEP00000012731 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.998 |
| COQ4 | DEDD | ENSNLEP00000021311 | ENSNLEP00000017056 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | Death effector domain containing. | 0.602 |
| DEDD | CASP10 | ENSNLEP00000017056 | ENSNLEP00000008472 | Death effector domain containing. | Caspase 10; Belongs to the peptidase C14A family. | 0.571 |
| DEDD | CASP8 | ENSNLEP00000017056 | ENSNLEP00000040588 | Death effector domain containing. | Caspase 8; Belongs to the peptidase C14A family. | 0.764 |
| DEDD | CFLAR | ENSNLEP00000017056 | ENSNLEP00000008469 | Death effector domain containing. | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | 0.590 |
| DEDD | COQ4 | ENSNLEP00000017056 | ENSNLEP00000021311 | Death effector domain containing. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.602 |
| DEDD | ENSNLEP00000047906 | ENSNLEP00000017056 | ENSNLEP00000047906 | Death effector domain containing. | Exonuclease domain-containing protein. | 0.576 |
| DEDD | ERI1 | ENSNLEP00000017056 | ENSNLEP00000030169 | Death effector domain containing. | Exoribonuclease 1. | 0.607 |
| DEDD | FADD | ENSNLEP00000017056 | ENSNLEP00000012731 | Death effector domain containing. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.677 |
