STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FLNAFilamin A. (2626 aa)    
Predicted Functional Partners:
FBLIM1
Uncharacterized protein.
   
 0.994
GP1BA
Glycoprotein Ib platelet subunit alpha.
    
 0.988
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.980
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.978
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 0.972
PAK1
Non-specific serine/threonine protein kinase.
    
 0.966
FLNB
Filamin B.
  
 
0.958
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
    
 0.944
VCL
Vinculin.
   
 
 0.944
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]
   
 
 0.933
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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