Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FLNAFilamin A. (2626 aa)    
Predicted Functional Partners:
FLNB
Filamin B.
  
 
0.998
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.987
PAK1
Non-specific serine/threonine protein kinase.
    
 0.978
FBLIM1
Uncharacterized protein.
   
 0.967
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
    
 0.963
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.954
TLN1
Talin 1.
   
 
 0.952
ENSNLEP00000026165
Uncharacterized protein.
   
 0.947
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 0.928
CAMK2G
Calcium/calmodulin dependent protein kinase II gamma.
    
 0.927
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (16%) [HD]