Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NCLUncharacterized protein. (632 aa)    
Predicted Functional Partners:
HNRNPU
B30.2/SPRY domain-containing protein.
   
 
 0.913
NPM1
Nucleophosmin 1.
   
 
 0.902
ENSNLEP00000027802
Uncharacterized protein.
   
 
 0.902
ENSNLEP00000029090
Uncharacterized protein.
   
 
 0.902
ENSNLEP00000036988
Nucleoplasmin domain-containing protein.
   
 
 0.902
ENSNLEP00000039968
Nucleoplasmin domain-containing protein.
   
 
 0.902
G1RDL6_NOMLE
Uncharacterized protein.
   
 
 0.882
LOC100584516
Uncharacterized protein.
   
 
 0.882
EIF3A
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]
   
 
 0.881
SERBP1
SERPINE1 mRNA binding protein 1.
   
 
 0.874
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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