| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT1 | ESR1 | ENSNLEP00000028045 | ENSNLEP00000018707 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.991 |
| AKT1 | ESR2 | ENSNLEP00000028045 | ENSNLEP00000017213 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Estrogen receptor 2. | 0.967 |
| AKT1 | FOS | ENSNLEP00000028045 | ENSNLEP00000047435 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.520 |
| AKT1 | SRC | ENSNLEP00000028045 | ENSNLEP00000048569 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Tyrosine-protein kinase. | 0.921 |
| ESR1 | AKT1 | ENSNLEP00000018707 | ENSNLEP00000028045 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.991 |
| ESR1 | ESR2 | ENSNLEP00000018707 | ENSNLEP00000017213 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Estrogen receptor 2. | 0.999 |
| ESR1 | FOS | ENSNLEP00000018707 | ENSNLEP00000047435 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.988 |
| ESR1 | MED1 | ENSNLEP00000018707 | ENSNLEP00000000991 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.997 |
| ESR1 | NCOA1 | ENSNLEP00000018707 | ENSNLEP00000047649 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor coactivator. | 0.997 |
| ESR1 | NCOA2 | ENSNLEP00000018707 | ENSNLEP00000013823 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor coactivator. | 0.995 |
| ESR1 | NCOA3 | ENSNLEP00000018707 | ENSNLEP00000008440 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor coactivator. | 0.999 |
| ESR1 | NCOR1 | ENSNLEP00000018707 | ENSNLEP00000017988 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor corepressor 1. | 0.996 |
| ESR1 | SP1 | ENSNLEP00000018707 | ENSNLEP00000021481 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Sp1 transcription factor. | 0.997 |
| ESR1 | SRC | ENSNLEP00000018707 | ENSNLEP00000048569 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Tyrosine-protein kinase. | 0.997 |
| ESR2 | AKT1 | ENSNLEP00000017213 | ENSNLEP00000028045 | Estrogen receptor 2. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.967 |
| ESR2 | ESR1 | ENSNLEP00000017213 | ENSNLEP00000018707 | Estrogen receptor 2. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.999 |
| ESR2 | FOS | ENSNLEP00000017213 | ENSNLEP00000047435 | Estrogen receptor 2. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.974 |
| ESR2 | MED1 | ENSNLEP00000017213 | ENSNLEP00000000991 | Estrogen receptor 2. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.991 |
| ESR2 | NCOA1 | ENSNLEP00000017213 | ENSNLEP00000047649 | Estrogen receptor 2. | Nuclear receptor coactivator. | 0.995 |
| ESR2 | NCOA2 | ENSNLEP00000017213 | ENSNLEP00000013823 | Estrogen receptor 2. | Nuclear receptor coactivator. | 0.983 |
