Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GLRXGlutaredoxin. (106 aa)    
Predicted Functional Partners:
RRM1
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.888
GSR
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.781
TXNRD1
Thioredoxin reductase 1.
  
 0.750
RRM2B
Ribonucleotide reductase regulatory TP53 inducible subunit M2B.
     
 0.705
GLRX5
Glutaredoxin 5.
      
 0.671
TXNRD2
Thioredoxin reductase 2.
  
 0.620
GPX7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
 0.620
GPX2
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
 0.619
TXNRD3
Thioredoxin reductase 3.
  
 0.618
SULT1C2
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.616
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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