Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MPZMyelin protein zero. (248 aa)    
Predicted Functional Partners:
EGR2
Early growth response 2.
    
 
 0.680
SH3TC2
SH3 domain and tetratricopeptide repeats 2.
      
 0.679
NRG1
Neuregulin 1.
      
 0.652
OPALIN
Oligodendrocytic myelin paranodal and inner loop protein.
      
 0.635
LITAF
LITAF domain-containing protein.
      
 0.608
MBP
Uncharacterized protein.
   
  
 0.584
PLP1
Proteolipid protein 1.
   
  
 0.564
THBD
Thrombomodulin.
      
 0.549
PPP2R5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
      
 0.491
GJB1
CNX domain-containing protein.
      
 0.490
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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