Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)    
Predicted Functional Partners:
GNAQ
G protein subunit alpha q.
    
 0.969
GNA14
G protein subunit alpha 14.
    
 0.967
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
   
 0.958
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
   
 0.957
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
   
 0.957
GNA15
G protein subunit alpha 15.
    
 0.944
GNB3
G protein subunit beta 3.
    
 0.936
GNAO1
G protein subunit alpha o1.
   
 0.932
GNAI2
G protein subunit alpha i2.
   
 0.932
GNAI1
G protein subunit alpha i1.
   
 0.932
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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