STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMLUncharacterized protein. (873 aa)    
Predicted Functional Partners:
RARA
Retinoic acid receptor alpha.
    
 0.995
SPI1
Spi-1 proto-oncogene.
    
 0.988
SUMO1
Small ubiquitin-related modifier.
    
 0.977
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.965
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
 0.948
SP100
SP100 nuclear antigen.
   
 
 0.918
EP300
E1A binding protein p300.
    
 0.915
CREBBP
CREB binding protein.
    
 0.866
HIPK2
Homeodomain interacting protein kinase 2.
    
 
 0.823
LOC100580143
RING-type domain-containing protein.
    
 
 0.820
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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