STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCNBHLH domain-containing protein. (442 aa)    
Predicted Functional Partners:
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
    
 
 0.975
MAX
MYC associated factor X.
    
0.975
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
    
0.928
NMI
N-myc and STAT interactor.
    
 
 0.824
ALK
Uncharacterized protein.
    
 0.822
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
    
 
 0.818
KPNB1
Karyopherin subunit beta 1.
    
 0.736
FBXW7
F-box and WD repeat domain containing 7.
    
 0.732
SCAP
SREBF chaperone.
   
 0.729
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.729
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.