node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IFNG | IL10 | ENSNLEP00000004233 | ENSNLEP00000033936 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 10. | 0.935 |
IFNG | IL1A | ENSNLEP00000004233 | ENSNLEP00000002245 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-1; Belongs to the IL-1 family. | 0.782 |
IFNG | IL1B | ENSNLEP00000004233 | ENSNLEP00000044905 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.928 |
IFNG | IL1R1 | ENSNLEP00000004233 | ENSNLEP00000023655 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 1 receptor type 1. | 0.537 |
IFNG | IL1R2 | ENSNLEP00000004233 | ENSNLEP00000017748 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 1 receptor type 2. | 0.585 |
IFNG | IL1RN | ENSNLEP00000004233 | ENSNLEP00000002424 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-1. | 0.461 |
IFNG | IL6 | ENSNLEP00000004233 | ENSNLEP00000047139 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Uncharacterized protein. | 0.858 |
IFNG | IL6R | ENSNLEP00000004233 | ENSNLEP00000035711 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 6 receptor. | 0.592 |
IFNG | TNF | ENSNLEP00000004233 | ENSNLEP00000047690 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.837 |
IL10 | IFNG | ENSNLEP00000033936 | ENSNLEP00000004233 | Interleukin 10. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.935 |
IL10 | IL1A | ENSNLEP00000033936 | ENSNLEP00000002245 | Interleukin 10. | Interleukin-1; Belongs to the IL-1 family. | 0.791 |
IL10 | IL1B | ENSNLEP00000033936 | ENSNLEP00000044905 | Interleukin 10. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.892 |
IL10 | IL1R1 | ENSNLEP00000033936 | ENSNLEP00000023655 | Interleukin 10. | Interleukin 1 receptor type 1. | 0.722 |
IL10 | IL1R2 | ENSNLEP00000033936 | ENSNLEP00000017748 | Interleukin 10. | Interleukin 1 receptor type 2. | 0.651 |
IL10 | IL1RN | ENSNLEP00000033936 | ENSNLEP00000002424 | Interleukin 10. | Interleukin-1. | 0.720 |
IL10 | IL6 | ENSNLEP00000033936 | ENSNLEP00000047139 | Interleukin 10. | Uncharacterized protein. | 0.981 |
IL10 | IL6R | ENSNLEP00000033936 | ENSNLEP00000035711 | Interleukin 10. | Interleukin 6 receptor. | 0.594 |
IL10 | TNF | ENSNLEP00000033936 | ENSNLEP00000047690 | Interleukin 10. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.861 |
IL1A | IFNG | ENSNLEP00000002245 | ENSNLEP00000004233 | Interleukin-1; Belongs to the IL-1 family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.782 |
IL1A | IL10 | ENSNLEP00000002245 | ENSNLEP00000033936 | Interleukin-1; Belongs to the IL-1 family. | Interleukin 10. | 0.791 |