Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMOTAngiomotin. (1088 aa)    
Predicted Functional Partners:
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
    
 0.996
NF2
Neurofibromin 2.
    
 0.995
PATJ
PATJ crumbs cell polarity complex component.
    
 0.991
YAP1
Uncharacterized protein.
    
 0.991
WWTR1
WW domain containing transcription regulator 1.
    
 0.989
ARHGAP17
Rho GTPase activating protein 17.
    
 0.986
AMOTL1
Angiomotin like 1.
   
 
0.981
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
    
 0.979
LATS1
Large tumor suppressor kinase 1.
    
 0.964
LATS2
Non-specific serine/threonine protein kinase.
    
 0.952
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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