Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa)    
Predicted Functional Partners:
SIX1
SIX homeobox 1.
   
 0.860
GJB2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.806
SIX2
SIX homeobox 2.
   
 0.745
PRRG1
Proline rich and Gla domain 1.
      
 0.698
G1QP80_NOMLE
Uncharacterized protein.
   
 0.690
DACH1
Dachshund family transcription factor 1.
    
 
 0.639
DACH2
Dachshund family transcription factor 2.
    
 
 0.639
PAX8
Paired box 8.
    
 0.635
TECTB
Tectorin beta.
      
 0.627
EYA2
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
     
  0.614
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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