STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TWNKTwinkle mtDNA helicase. (678 aa)    
Predicted Functional Partners:
SSBP1
Single stranded DNA binding protein 1.
   
  
 0.871
POLG
DNA polymerase gamma, catalytic subunit.
   
  
 0.854
SLC25A4
Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.707
TFAM
Transcription factor A, mitochondrial.
      
 0.696
POLG2
DNA polymerase gamma 2, accessory subunit.
      
 0.692
DGUOK
Deoxyguanosine kinase.
      
 0.690
MPV17
Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.688
POLRMT
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
  
 0.683
RRM2B
Ribonucleotide reductase regulatory TP53 inducible subunit M2B.
      
 0.680
ENSNLEP00000033113
Uncharacterized protein.
      
 0.678
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.