STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.999
CTNNB1
Catenin beta 1.
   
 0.999
RBX1
Ring-box 1.
    
 0.999
NFKBIA
NFKB inhibitor alpha.
    
 0.998
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.998
PER2
Period circadian regulator 2.
    
 0.992
APC
APC regulator of WNT signaling pathway.
    
 0.992
WWTR1
WW domain containing transcription regulator 1.
    
 0.987
ENSNLEP00000029811
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.986
YAP1
Uncharacterized protein.
    
 0.986
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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