Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)    
Predicted Functional Partners:
FBXW11
F-box and WD repeat domain containing 11.
  
0.999
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.998
CTNNB1
Catenin beta 1.
   
 0.998
RBX1
Ring-box 1.
    
 0.997
FBXO5
F-box protein 5.
    
 0.996
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.994
WWTR1
WW domain containing transcription regulator 1.
    
 0.992
PER2
Period circadian regulator 2.
    
 0.987
GLI3
GLI family zinc finger 3.
    
 0.983
GLI1
GLI family zinc finger 1.
    
 0.982
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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