| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AK9 | CTPS1 | ENSNLEP00000015410 | ENSNLEP00000014876 | Adenylate kinase 9. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.939 |
| AK9 | CTPS2 | ENSNLEP00000015410 | ENSNLEP00000011604 | Adenylate kinase 9. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.939 |
| AK9 | ENSNLEP00000030795 | ENSNLEP00000015410 | ENSNLEP00000030795 | Adenylate kinase 9. | Thymidylate_kin domain-containing protein. | 0.951 |
| AK9 | ITPA | ENSNLEP00000015410 | ENSNLEP00000009225 | Adenylate kinase 9. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.933 |
| AK9 | NME7 | ENSNLEP00000015410 | ENSNLEP00000018190 | Adenylate kinase 9. | Nucleoside diphosphate kinase 7; Belongs to the NDK family. | 0.952 |
| AK9 | RRM1 | ENSNLEP00000015410 | ENSNLEP00000021038 | Adenylate kinase 9. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.977 |
| CTPS1 | AK9 | ENSNLEP00000014876 | ENSNLEP00000015410 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Adenylate kinase 9. | 0.939 |
| CTPS1 | CTPS2 | ENSNLEP00000014876 | ENSNLEP00000011604 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.992 |
| CTPS1 | ITPA | ENSNLEP00000014876 | ENSNLEP00000009225 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.602 |
| CTPS1 | NME7 | ENSNLEP00000014876 | ENSNLEP00000018190 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase 7; Belongs to the NDK family. | 0.941 |
| CTPS2 | AK9 | ENSNLEP00000011604 | ENSNLEP00000015410 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Adenylate kinase 9. | 0.939 |
| CTPS2 | CTPS1 | ENSNLEP00000011604 | ENSNLEP00000014876 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.992 |
| CTPS2 | ITPA | ENSNLEP00000011604 | ENSNLEP00000009225 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.602 |
| CTPS2 | NME7 | ENSNLEP00000011604 | ENSNLEP00000018190 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase 7; Belongs to the NDK family. | 0.941 |
| ENSNLEP00000030795 | AK9 | ENSNLEP00000030795 | ENSNLEP00000015410 | Thymidylate_kin domain-containing protein. | Adenylate kinase 9. | 0.951 |
| ENSNLEP00000030795 | NME7 | ENSNLEP00000030795 | ENSNLEP00000018190 | Thymidylate_kin domain-containing protein. | Nucleoside diphosphate kinase 7; Belongs to the NDK family. | 0.948 |
| ENSNLEP00000030795 | RRM1 | ENSNLEP00000030795 | ENSNLEP00000021038 | Thymidylate_kin domain-containing protein. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.947 |
| ITPA | AK9 | ENSNLEP00000009225 | ENSNLEP00000015410 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Adenylate kinase 9. | 0.933 |
| ITPA | CTPS1 | ENSNLEP00000009225 | ENSNLEP00000014876 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.602 |
| ITPA | CTPS2 | ENSNLEP00000009225 | ENSNLEP00000011604 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.602 |
