STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL4BCullin 4B; Belongs to the cullin family. (913 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.999
CUL4A
Cullin 4A; Belongs to the cullin family.
  
 
0.996
RBX1
Ring-box 1.
    
 0.996
DCAF1
DDB1 and CUL4 associated factor 1.
   
 0.993
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.990
DDB2
Damage specific DNA binding protein 2.
    
 0.981
CRBN
Cereblon.
    
 0.981
CAND1
Cullin associated and neddylation dissociated 1.
   
 0.979
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.979
COPS2
COP9 signalosome subunit 2.
  
 0.964
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.