Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2104 aa)    
Predicted Functional Partners:
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
   
 
 0.948
LRCH1
Leucine rich repeats and calponin homology domain containing 1.
   
 
 0.931
CDC42
Cell division cycle 42.
   
 0.863
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.851
DOCK8
Dedicator of cytokinesis 8; Belongs to the DOCK family.
    
   0.834
LRCH2
Leucine rich repeats and calponin homology domain containing 2.
   
 
 0.751
RHOJ
Ras homolog family member J.
   
 0.696
GRB2
Growth factor receptor bound protein 2.
   
 0.693
DOCK6
Dedicator of cytokinesis 6; Belongs to the DOCK family.
    
   0.683
RHOQ
Uncharacterized protein.
   
 0.651
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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