STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XIAPX-linked inhibitor of apoptosis. (497 aa)    
Predicted Functional Partners:
CASP9
Caspase 9; Belongs to the peptidase C14A family.
   
 0.998
CASP3
Caspase 3; Belongs to the peptidase C14A family.
   
 0.998
DIABLO
Uncharacterized protein.
    
 0.997
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.996
HTRA2
HtrA serine peptidase 2.
    
 0.994
BIRC2
Baculoviral IAP repeat containing 2.
    
0.992
CASP7
Caspase 7; Belongs to the peptidase C14A family.
   
 0.988
BIRC3
Baculoviral IAP repeat containing 3.
    
0.982
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.976
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
    
 0.975
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.