STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100604016DEFSN domain-containing protein. (64 aa)    
Predicted Functional Partners:
DEFB1
Defensin beta 1.
   
 
 0.975
CCR2
C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity).
     
 0.822
CCRL2
C-C motif chemokine receptor like 2; Belongs to the G-protein coupled receptor 1 family.
     
 0.693
DEFA5
Defensin alpha 5.
     
 0.658
G1QHT6_NOMLE
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.628
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
      
 0.568
CCR3
C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.
     
 0.550
LOC100584372
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.550
LOC100590398
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.530
LOC101179385
Protein S100; Belongs to the S-100 family.
   
  
 0.520
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.