Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LATS1Large tumor suppressor kinase 1. (1130 aa)    
Predicted Functional Partners:
LATS2
Non-specific serine/threonine protein kinase.
  
 
0.998
WWTR1
WW domain containing transcription regulator 1.
   
 0.998
MOB1B
MOB kinase activator 1B.
   
 0.997
STK3
Serine/threonine kinase 3.
    
0.997
YAP1
Uncharacterized protein.
   
 0.995
MOB1A
MOB kinase activator 1A.
    
 0.991
NF2
Neurofibromin 2.
    
 
 0.990
SAV1
Salvador family WW domain containing protein 1.
    
 0.984
LIMD1
LIM domains containing 1.
    
 0.975
AMOT
Angiomotin.
    
 0.964
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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