Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGSF1Immunoglobulin superfamily member 1. (1341 aa)    
Predicted Functional Partners:
ACVR1B
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 0.906
ACVR1
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
  0.903
FCER1G
Uncharacterized protein.
   
 0.617
ENSNLEP00000042959
Uncharacterized protein.
  
 
 0.594
TNFSF11
Tumor necrosis factor ligand superfamily member.
   
  
 0.513
VSIG10L
V-set and immunoglobulin domain containing 10 like.
      
 0.493
MBOAT7
Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family.
    
 
 0.493
LENG1
Leukocyte receptor cluster member 1.
     
 0.490
CNOT3
CCR4-NOT transcription complex subunit 3.
      
 0.478
DHX40
Uncharacterized protein.
  
     0.454
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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